HIV-like viruses in non-human primates have existed much longer than previously thought

Public release date: 24-Jan-2013
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Contact: Gina Alvino
galvino@plos.org
Public Library of Science

Viruses similar to those that cause AIDS in humans were present in non-human primates in Africa at least 5 million years ago and perhaps up to 12 million years ago, according to study published January 24 in the Open Access journal PLOS Pathogens by scientists at Fred Hutchinson Cancer Research Center. Until now, researchers have hypothesized that such viruses originated much more recently.

HIV-1, the virus responsible for AIDS, infiltrated the human population in the early 20th century following multiple transmissions of a similar chimpanzee virus known as SIVcpz. Previous work to determine the age of HIV-like viruses, called lentiviruses, by comparing their genetic blueprints has calculated their origin to be tens of thousands of years ago.

However, other researchers have suspected this time frame to be much too recent. Michael Emerman, Ph.D., a virologist and member of the Human Biology Division at Fred Hutchinson Cancer Research Center, and Alex Compton, a graduate student in the Emerman Lab, describe the use of a technique to estimate the extent to which primates and lentiviruses have coexisted by tracking the changes in a host immunity gene called APOBEC3G that were induced by ancient viral challenges.

They report that this host immunity factor is evolving in tandem with a viral gene that defends the virus against APOBEC3G, which allowed them to determine the minimum age for the association between primates and lentiviruses to be around 5 or 6 million years ago, and possibly up to 12 million years ago.

These findings suggest that HIV-like infections in primates are much older than previously thought, and they have driven selective changes in antiviral genes that have incited an evolutionary arms race that continues to this day. The study also confirms that viruses similar to HIV that are present in various monkey species today are the descendants of ancient pathogens in primates that have shaped how the immune system fights infections.

"More than 40 non-human primate species in sub-Saharan Africa are infected with strains of HIV-related viruses," Emerman said. "Since some of these viruses may have the potential to infect humans as well, it is important to know their origins."

###

FINANCIAL DISCLOSURE: This work was supported by R01 A130937 (to ME) and an NSF Graduate Research Fellowship and NIH Training Grant in Viral Pathogenesis T32AI083203 (to AAC). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

COMPETING INTERESTS: The authors have declared that no competing interests exist.

PLEASE ADD THIS LINK TO THE PUBLISHED ARTICLE IN ONLINE VERSIONS OF YOUR REPORT: http://dx.plos.org/10.1371/journal.ppat.1003135 (link will go live upon embargo lift)

CITATION: Compton AA, Emerman M (2013) Convergence and Divergence in the Evolution of the APOBEC3G-Vif Interaction Reveal Ancient Origins of Simian Immunodeficiency Viruses. PLoS Pathog 9(1): e1003135. doi:10.1371/journal.ppat.1003135

Institutional Contact:
Kristen Lidke Woodward
(206) 667-5095
kwoodwar@fhcrc.org

Disclaimer

This press release refers to an upcoming article in PLOS Pathogens. The release is provided by the article authors. Any opinions expressed in these releases or articles are the personal views of the journal staff and/or article contributors, and do not necessarily represent the views or policies of PLOS. PLOS expressly disclaims any and all warranties and liability in connection with the information found in the releases and articles and your use of such information.

Media Permissions

PLOS Journals publish under a Creative Commons Attribution License, which permits free reuse of all materials published with the article, so long as the work is cited (e.g., Kaltenbach LS et al. (2007) Huntingtin Interacting Proteins Are Genetic Modifiers of Neurodegeneration. PLoS Genet 3(5): e82. doi:10.1371/journal.pgen.0030082). No prior permission is required from the authors or publisher. For queries about the license, please contact the relative journal contact indicated here: http://www.plos.org/about/media-inquiries/.

About PLOS Pathogens

PLOS Pathogens publishes outstanding original articles that significantly advance the understanding of pathogens and how they interact with their host organisms. All works published in PLOS Pathogens are open access. Everything is immediately available subject only to the condition that the original authorship and source are properly attributed. Copyright is retained by the authors. The Public Library of Science uses the Creative Commons Attribution License.

About the Public Library of Science

The Public Library of Science (PLOS) is a non-profit organization of scientists and physicians committed to making the world's scientific and medical literature a freely available public resource. For more information, visit http://www.plos.org.

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Public release date: 24-Jan-2013
[ | E-mail | Share ]

Contact: Gina Alvino
galvino@plos.org
Public Library of Science

Viruses similar to those that cause AIDS in humans were present in non-human primates in Africa at least 5 million years ago and perhaps up to 12 million years ago, according to study published January 24 in the Open Access journal PLOS Pathogens by scientists at Fred Hutchinson Cancer Research Center. Until now, researchers have hypothesized that such viruses originated much more recently.

HIV-1, the virus responsible for AIDS, infiltrated the human population in the early 20th century following multiple transmissions of a similar chimpanzee virus known as SIVcpz. Previous work to determine the age of HIV-like viruses, called lentiviruses, by comparing their genetic blueprints has calculated their origin to be tens of thousands of years ago.

However, other researchers have suspected this time frame to be much too recent. Michael Emerman, Ph.D., a virologist and member of the Human Biology Division at Fred Hutchinson Cancer Research Center, and Alex Compton, a graduate student in the Emerman Lab, describe the use of a technique to estimate the extent to which primates and lentiviruses have coexisted by tracking the changes in a host immunity gene called APOBEC3G that were induced by ancient viral challenges.

They report that this host immunity factor is evolving in tandem with a viral gene that defends the virus against APOBEC3G, which allowed them to determine the minimum age for the association between primates and lentiviruses to be around 5 or 6 million years ago, and possibly up to 12 million years ago.

These findings suggest that HIV-like infections in primates are much older than previously thought, and they have driven selective changes in antiviral genes that have incited an evolutionary arms race that continues to this day. The study also confirms that viruses similar to HIV that are present in various monkey species today are the descendants of ancient pathogens in primates that have shaped how the immune system fights infections.

"More than 40 non-human primate species in sub-Saharan Africa are infected with strains of HIV-related viruses," Emerman said. "Since some of these viruses may have the potential to infect humans as well, it is important to know their origins."

###

FINANCIAL DISCLOSURE: This work was supported by R01 A130937 (to ME) and an NSF Graduate Research Fellowship and NIH Training Grant in Viral Pathogenesis T32AI083203 (to AAC). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

COMPETING INTERESTS: The authors have declared that no competing interests exist.

PLEASE ADD THIS LINK TO THE PUBLISHED ARTICLE IN ONLINE VERSIONS OF YOUR REPORT: http://dx.plos.org/10.1371/journal.ppat.1003135 (link will go live upon embargo lift)

CITATION: Compton AA, Emerman M (2013) Convergence and Divergence in the Evolution of the APOBEC3G-Vif Interaction Reveal Ancient Origins of Simian Immunodeficiency Viruses. PLoS Pathog 9(1): e1003135. doi:10.1371/journal.ppat.1003135

Institutional Contact:
Kristen Lidke Woodward
(206) 667-5095
kwoodwar@fhcrc.org

Disclaimer

This press release refers to an upcoming article in PLOS Pathogens. The release is provided by the article authors. Any opinions expressed in these releases or articles are the personal views of the journal staff and/or article contributors, and do not necessarily represent the views or policies of PLOS. PLOS expressly disclaims any and all warranties and liability in connection with the information found in the releases and articles and your use of such information.

Media Permissions

PLOS Journals publish under a Creative Commons Attribution License, which permits free reuse of all materials published with the article, so long as the work is cited (e.g., Kaltenbach LS et al. (2007) Huntingtin Interacting Proteins Are Genetic Modifiers of Neurodegeneration. PLoS Genet 3(5): e82. doi:10.1371/journal.pgen.0030082). No prior permission is required from the authors or publisher. For queries about the license, please contact the relative journal contact indicated here: http://www.plos.org/about/media-inquiries/.

About PLOS Pathogens

PLOS Pathogens publishes outstanding original articles that significantly advance the understanding of pathogens and how they interact with their host organisms. All works published in PLOS Pathogens are open access. Everything is immediately available subject only to the condition that the original authorship and source are properly attributed. Copyright is retained by the authors. The Public Library of Science uses the Creative Commons Attribution License.

About the Public Library of Science

The Public Library of Science (PLOS) is a non-profit organization of scientists and physicians committed to making the world's scientific and medical literature a freely available public resource. For more information, visit http://www.plos.org.

---

[ | E-mail | Share ]

?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Source: http://www.eurekalert.org/pub_releases/2013-01/plos-hvi012213.php

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LinkedIn Ads | Linkedin Ads PPC Marketing

Since its inception back in July of 2008, LinkedIn Ads has caught the eye of many B2B advertisers who are looking for another vehicle to reach a very specific audience. In recent news, Linkedin has reached over 200 million users and continues to to be a force to be reckoned with. So with no further ado, Acquisio is proud to present an Exclusive Online Interview with Will Hambly,?Online Marketing Manager with LinkedIn.

?

Question #1: Now that LinkedIn has over 200 Million Users worldwide, are there any plans to expand or enhance the LinkedIn Ads platform?

Answer: As we grow there are tremendous network effects that benefit our members as well as all three business lines. Looking at our self-serve LinkedIn Ads business, the main difference that advertisers are already seeing is incremental reach. In addition to that, we?ve made a number of enhancements to our self-serve advertising platform over the last year, including launching 18 additional languages, new targeting facets, enhanced audience intelligence features, multi currency rollout, and most recently, our first self-serve video format.

Question #2: LinkedIn Ads has a vast array of targeting abilities for advertisers. Can you tell which ones are used most often? Which ones have the biggest benefit?

Answer: One of the main reasons advertisers come to LinkedIn is to take advantage of the rich targeting options we provide. Some of the most commonly used targeting facets are Job Function, Job Title, and Industry because they allow marketers to reach specific influencers and decision makers within their target market.

Question #3: In PPC Marketing, Google and Bing Ads are the traditional platforms most advertisers are familiar with. What can you tell us about the LinkedIn Ads that may persuade them to give it a try?

Answer: LinkedIn offers distinct value in its targeting capabilities, audience, and context. Professional identity is top of mind for LinkedIn members, so if you?re marketing a B2B product or service, there?s no similar place to reach people in that mindset on the web.

Question #4: As with Facebook Ads, advertisers can choose from a wide variety of audience types (Demographics, Interests, etc?) From your perspective, where is LinkedIn unique benefits for advertisers LinkedIn Ads?

Answer:? LinkedIn is the best place for brands to accelerate their marketing efforts. We have a more influential, affluent, and educated member base than any other social network in the world. Our professional context attracts members who are in a purposeful mindset, which is a desirable environment for marketers who want to target highly engaged and receptive audiences.

Question #5:?If there is one (1) thing that LinkedIn Ads could do better or different, what would that be?
Answer:? One area is making our self-serve advertising platform easier to use as we?ve grown the number of features and targeting options. Advertisers have a strong sense of who their trying to reach, because they understand their business the best, but translating that into professional targeting facets is not necessarily as straightforward.

Question #6: Which Industries and/or Audiences would be a good fit for LinkedIn Ads? Are there ones that are not?

Answer: B2B is definitely our strength and we?re particularly strong in technology, financial services, and education. You don?t have to be in one of those categories to be successful, so I?d encourage any advertiser that is looking to reach professional audiences to start by creating a Company Page and then amplify that presence with LinkedIn Ads.

In Conclusion:

The benefit of using LinkedIn Ads is not based on a standard PPC Strategy, but rather more of ?outside the box? audience-based testing. Depending on the industry, just as with using Facebook Ads, it?s the idea of indirectly targeting specific demographics that are not available with standard PPC Marketing. Furthermore, for this strategy to be successful, it requires a deep understanding into the behavior and mindset of the customers.

Source: http://www.acquisio.com/ppc/exclusive-interview-with-will-hamby-from-linkedin/

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Scope of U.S. Air Force sexual assault case "stunning:" general

WASHINGTON (Reuters) - The sexual assault of 59 military recruits by drill instructors at a Texas air base was a "stunning" case that cannot be allowed to happen again, the top U.S. Air Force general told lawmakers on Wednesday as he testified before Congress about steps to address the problem.

But victims groups at a hearing on the attacks at Lackland Air Force Base in San Antonio said the incident was just the latest example of a sexual assault problem that has bedeviled the military for decades. They said the military had failed to fully address the problem for far too long.

The Armed Services Committee in the Republican-led House of Representatives agreed to hold the hearing on the unfolding scandal at Lackland after being urged to do so by nearly 80 lawmakers.

"How could this have happened? How could the system and in particular the leadership have failed to protect the men and women who serve our nation from sexual predators?" asked Representative Buck McKeon, the panel's chairman.

"The events at Lackland are the most recent example of sexual assaults that have plagued our military for far too long," he said.

The military has been grappling with the issue since the 1991 Tailhook scandal, when dozens of Marine Corps and Navy aviators were accused of sexually assaulting 83 women and 7 men at a convention in Las Vegas.

The latest Pentagon report on sexual assault in the military, released in April 2012, said 3,192 cases were reported in the fiscal year that ended September 30, 2011. That was a 1 percent increase in reporting from the previous fiscal year.

Defense Secretary Leon Panetta, who has tried to make curbing sexual assault a priority, has said there could be as many as 19,000 cases a year, a number he called "unacceptable."

The Lackland sexual assaults came to light in June 2011 when a female recruit reported that a drill sergeant had sexually assaulted a fellow trainee. The resulting investigation found that the instructor had attacked 10 victims between October 2010 and June 2011.

During the course of the investigation, three other drill instructors approached their squadron superintendent and said they knew of other instructors who were engaging in inappropriate conduct with their trainees, prompting another investigation.

General Edward Rice, who is responsible for recruiting and training Air Force personnel, said so far eight drill sergeants have received disciplinary action for sexual misconduct, nine have been charged and are facing courts martial and 15 are still under investigation.

Rice said 59 "victims or alleged victims" had been identified and offered support services, which all but two had accepted.

The Air Force chief of staff, General Mark Welsh, said the scope of the Lackland scandal was shocking.

"This collection of events at basic military training has been stunning to most of us in the Air Force," he said. "There's simply no excuse for it, there's no justifiable explanation and there is no way we can allow this to happen again."

RESPONSE CALLED INADEQUATE

He and Rice said the Air Force had implemented half of the 46 recommendations made by Major General Margaret Woodward, who investigated the Lackland situation at the commander's request.

Another 22 recommendations will be completed by November this year and the final one - for a shorter basic training period - is being considered separately.

Victims' advocates who attended the hearing said the military's response to Lackland was inadequate and was unlikely to stop the problem of sexual assaults in the military or even to ensure impartial investigation and prosecution of the crime.

"The military is not able to solve this problem," said attorney Susan Burke, who has represented victims of military sexual assault. "They have had decades. The definition of insanity is to do the same thing again and again and expect a different result."

Burke and other victims' advocates have called for lawmakers to change the way the military justice system handles rape and sexual assault charges.

"We need to have legislation passed by Congress in this session and we need that legislation to take justice, ... the judicatory power, out of the conflicted and biased hands of the chain of command and put it in impartial hands," she said.

Lawmakers also heard directly from victims of sexual assault, including retired Air Force Technical Sergeant Jennifer Norris, who told how she was raped once and assaulted three times in her first two years in the service.

She said she had a difficult time listening to the testimony by Welsh and Rice. While they may genuinely care about changing the system, they still rely on military justice that depends on commanders to "do the right thing," she said.

"In my eyes, that means, OK, commander, you're the judge, jury and executioner," she said. While the civilian legal system has different courts and routes of appeal, "in the military we have one person that may or may not help you," she said.

(Editing by Christopher Wilson)

Source: http://news.yahoo.com/scope-u-air-force-sexual-assault-case-stunning-002711711.html

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Louisiana's Online Lagniappe Covers Some Delicious Internet ...

Welcome back to another edition of Louisiana?s Online Lagniappe, where we cover the best of Louisiana-based companies doing online marketing right! Our office has been having a pretty intense debate on which King Cake is best, which appears to have taken its toll on our column since we ended up with three food and drink based companies. Let?s see what they?re up to.

The Southern Food and Beverage Museum

While we do enjoy highlighting companies using traditional social media in great ways in this column, we?re even more excited when Louisiana organizations try something out of the box. The Southern Food and Beverage Museum did just that when they launched their new Nitty Grits website. It?s currently a very simple (and happily responsive) website, but the plans to create an international culinary dictionary are ambitious to say the least. We wish the website as well as those behind it the best of luck!

?and while we?re at it, we?ll also compliment their use of traditional social media as well. Snappy, often updated content along with online-only contests are a great way to keep customers constantly checking social media profiles for the latest information.

Your Nutrition Delivered

As part of Idea Village?s IDEAxcelerator 2013 program, we?d expect nothing less than smart use of social media to promote their products and services. Your Nutrition Delivered, well, delivers on that promise! Numerous tweets per day not only discuss the company, but also give other helpful?nutritious?advice that would be useful to their customers. Their Facebook page also posts inspiration quotes every single day, and makes the smart choice to do it with pictures instead of simply updating their status with the words. Facebook?s own website notes that picture posts generate 120% more engagement than the average post. If your company is trying to figure out how to get your page?s fans more involved, follow Your Nutrition Delivered?s lead and take a more visual approach to social media.

Naked Pizza

I?m surprised it has taken us three issues of Louisiana?s Online Lagniappe to mention Naked Pizza. From way back in 2009, when they received national attention for posting their Twitter profile on their street sign, to their continued intelligence when it concerns social media ? Naked Pizza has always been at the forefront of making a company?s social presence all about the conversation. On Twitter they interact with customers, answer questions, make jokes with other pizza companies, and generally have a good time, all while making sure to maintain that brand tone and voice that is oh so important to a social media presence.

And the Lagniappe?s lagniappe

Our extra shout-out this week goes to whoever is manning the @KreweduVieux twitter account. After a dormant 2012, it?s come back alive with the sort of unprintable charm that only Krewe Du Vieux can manage. Here?s to hoping it stays active year-round!

Send In Your Lagniappe

Is your Louisiana-based business doing incredible things online? Drop me a note at?Flynn@onlineoptimism.com?and it might just be included in next week?s column.

Tags: Flynn Zaiger, idea village, Krewe Du Vieux, Louisiana Online Lagniappe, Louisiana's Online Lagniappe, Mardi Gras, Naked Pizza, New Orleans restaurants, Online Optimism, southern food and beverage museum, Your Nutrition Delivered

Category: Louisiana Online Lagniappe, Marketing, Social Media

Source: http://siliconbayounews.com/2013/01/24/louisianas-online-lagniappe-covers-some-delicious-internet-marketing/?utm_source=rss&utm_medium=rss&utm_campaign=louisianas-online-lagniappe-covers-some-delicious-internet-marketing

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Utah governor unveils outdoor recreation plan

SALT LAKE CITY (AP) ? Gov. Gary Herbert unveiled his long-awaited vision for outdoor recreation in the state Wednesday, calling for the creation of a government office devoted solely to the topic and laying out a broad-stroke plan to preserve Utah's natural jewels and cultivate outdoor recreation as a pillar of its economy.

Herbert revealed the plan a day after organizers of one of the world's largest outdoor gear trade announced they will keep the convention in Salt Lake City through 2016. The long-term future of the show, which is under way this week, remains murky though because of a shortage of convention floor space and lodging for convention-goers.

Herbert said Wednesday he hopes the biannual show ? which draws more than 20,000 people and pours an estimated $40 million into Utah's economy every year ? will make Salt Lake City its permanent home.

Organizers had threatened to move the event if the state didn't demonstrate its commitment to preserving public lands and solve the space issues. They asked Herbert in August to share his vision for the industry by January.

Herbert's plan calls for a new government office that would be devoted solely to outdoor recreation. Its duties would include organizing an annual summit where outdoor businesses, recreationalists and other stakeholders gather.

The plan also says Utah should stand by its desire to take control of federal lands. With or without the show, the principles in the plan will help to guide the state in balancing outdoor recreation and public lands, the governor noted.

"This is a pathway, a framework, for us to work together, despite some differences we may have," he said at a news conference.

The retail show is sponsored by the Boulder, Colo.-based Outdoor Industry Association, which represents companies such as Patagonia and The North Face.

Its president and CEO, Frank Hugelmeyer, lauded the governor for his commitment to making sure outdoor recreation and Utah's public lands are protected. He called Hebert's vision "unprecedented" and said it could serve as a blueprint for other states.

Hugelmeyer said the two-year extension of the show allows both sides to work on what are "pretty big issues" regarding the logistics of keeping Salt Lake City a viable location for the growing show. The governor's vision leaves some unresolved issues, he said, such as the state's desire to control federal lands. But, it includes mechanisms that will enable them to solve those issues in future years, he said.

The association opposed a bill signed by Herbert in March that demands the federal government relinquish control of public lands in Utah by 2014. It also opposes Utah's effort to open thousands of dirt paths across public lands to motor vehicles. But despite those differences, Hugelmeyer said Salt Lake City remains a great fit for the show.

"We're in the business of meaningful experiences, and Utah is one of the great places on the planet to have meaningful experiences," Hugelmeyer said.

Convention-goers crammed into the Salt Palace Convention Center Wednesday to look at hiking shoes, beanies, wool socks and countless other products used for outdoor recreation. People sat on the edges of a wide staircase while they ate lunch and looked at their computers.

Several retailers said they hope the show stays in Utah, but acknowledged that the state must solve the space and lodging issues. Robert Gardner, president and CEO of Joovy, said the show has a great vibe in Salt Lake City but said there's no way it can stay here beyond 2016 without more room for exhibitors. His company displayed its kid strollers and bikes in an exhibition tent at last summer's show.

"The tent was way better than I thought it would be, but it's still a tent," Gardner said.

Jay Rossbach, sales director for Hotmocs, had to stay at hotel in West Jordan, a Salt Lake City suburb about 15 miles south of the convention center. But he said he can't see the show anywhere else, and hopes more hotels are built in downtown Salt Lake City.

"Please don't put it in Vegas," said Rossbach, whose company sells beanies and neck gators.

Salt Lake City has plenty of nearby skiing and outdoor activities and is not too overwhelming for many who come from small mountain towns, said Taylor Mallard, marketing manager for Bozeman, Mont.-based Oboz Footwear.

"To me, Salt Lake makes perfect sense? minus the space issue," Mallard said. "It's like a mountain town, only bigger."

Two weeks ago, the state approved a $2.66 million grant to build a 150,000-square-foot exhibition tent near the city's convention center to add space for the show. Officials also are exploring temporary lodging options, including lodging at the University of Utah campus.

Sales of outdoor products and sporting goods bring $5.8 billion to Utah's economy every year and $60 million in state and local sales taxes. Utah's tourism is driven by visitors enjoying of the state's canyons, mountains and desert areas, and the state has highest the percentage of outdoor and sporting good jobs in the country.

Alan Matheson, the governor's environmental adviser, said the state also recognizes that easy access to outdoor activities attracts businesses in other industries, such as high-tech companies.

The state's new outdoors plan is a great first step, but now the details need to be hammered out, said Ashley Korenblat, president of Western Spirit Cycling in Moab, a mountain biking town that draws people from around the world. Korenblat said upcoming outdoor gear shows offer a chance to check in every six months see if the state is producing results.

"That will prohibit this vision from being another binder on the shelf just gathering dust," she said.

Though she finds the plan encouraging, she said the "elephant in the room" remains the state's federal lands grab. There's still a lot of industry concern with the way those lands would be managed if the state took control, she said.

Matheson said that if the state did control those spaces, it doesn't mean they'd sell them all off or use all the land for energy development.

"The people of Utah love these lands ? love our natural gems. And we're not going to do anything to lose those treasures," he said.

The governor, who is a big proponent of energy development, said the state would do a better job than the federal government of juggling the demands of the energy and outdoor industries.

"It should be a balanced approach," Herbert said. "Not everything should be protected, and not everything should be developed."

Herbert dodged a bullet by keeping the trade show in Utah, said one business leader who quit Herbert's outdoor recreation advisory council in protest over the Republican governor's policies.

"I think it's a meaningful first step," said Peter Metcalf, president and chief executive of Salt Lake City-based Black Diamond Inc., a manufacturer of outdoor gear. "It states how important outdoor recreation is to Utah ? our public lands, waterways and clean air.

"I'm gratified ? but now comes the real work," he said. "Utah has been ground zero for radical policies threatening our public lands."

___

Associated Press writer Paul Foy contributed to this report.

Source: http://news.yahoo.com/utah-governor-unveils-outdoor-recreation-plan-170125088--finance.html

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More Sense 5 screenshots spotted on a Droid DNA

 

Following today's leak of an unreleased version of Sense 5 running on the Droid DNA, we're now seeing more screenshots from users claiming to have their hands on the software as well. Member mdeejay at XDA has just put up several screenshots of what is said to be a stable build of Android 4.1.2 with Sense 5 running on the Verizon phone, as ported from -- wait for it -- a Sprint version of the rumored M7.

We're not sure if that answers more questions than it creates, but it certainly gives us a lot to think about. This probably isn't the last leak (or purported leak) we'll see in the coming weeks, as HTC is likely set to show off a number of new devices at MWC in February. You can take a gander at several more screenshots at the source link below.

Source: XDA

Source: http://feedproxy.google.com/~r/androidcentral/~3/baCliWIp3Fc/story01.htm

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Avoid Overhyping Everything with a "Fudge Zone"

When you're trying to convince a friend or co-worker that something is amazing, it's easy to overshoot and overhype something to the point they'll definitely be disappointed. To keep this from happening, author Dan Ariely recommends you create a "fudge zone."

We all overhype things we're excited about. Whether it's a movie, book, or even a project we're working on. The downside of overhyping is that when we tell our friends about it, we set unreasonable expectations that can't be met. In turn, our friends and co-workers end up not enjoying what we suggest as much as they should. Ariely recommends a pretty simple fix:

Here is how I view the issue: Heightened expectations can change our experience by (let's say) 20%, which means that as long as the increased expectations are within this range, the expectation can "pull" the experience and influence it. But when expectations are too extreme (let's say 60% heightened), the gap with reality becomes too wide, and they may backfire and reduce enjoyment.

If you want your friends to experience something as better than it truly is, go for it and exaggerate. But don't exaggerate by too much. This kind of "fudge zone" also suggests that in areas of life where people are not experts, you can exaggerate a bit more.

Setting high expectations isn't always a bad thing, and in fact, expectations can actually increase our enjoyment of everything, but you want to avoid overhyping something too much. While Ariely's point deals with you placing heightened expectations on what you recommend, the same can be done in reverse for your own expectation of enjoyment too.

Coming to Grips with Chips and Dips | Wall Street Journal

Photo by Justin.

Source: http://feeds.gawker.com/~r/lifehacker/full/~3/8Kw0wnhJwiw/avoid-overhyping-everything-with-a-fudge-zone

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